HSPMdb Accession No | HSPMDB002472 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 42 |
IUPAC Name | Ethyl 2-(2-morpholinoethylthio)-1-(2-oxo-2-phenylethyl)-pyrimidin-4-one-5-carboxylate |
SMILES | OC(=O)C1=CN=C2SC(=C(CN2C1=O)c3ccccc3)CN4CCOCC4 |
Class | Library of small molecule structures |
Ki (µM) | 16 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |