HSPMdb Accession No | HSPMDB002471 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 40 |
IUPAC Name | Ethyl-2-(2-oxo-2-(2-(2-phenylacetyl)hydrazinyl)ethylthio)-pyrimidin-4-one-5-carboxylate |
SMILES | CCOC(=O)C1=CN=C(NC1=O)SCCN2CCOCC2 |
Class | Library of small molecule structures |
Ki (µM) | 17 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |