HSPMdb Accession No | HSPMDB002470 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 38 |
IUPAC Name | 1-Benzyl-2-(2-morpholino-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide |
SMILES | C(C1=CC=CC=C1)N1C(=NC=C(C1=O)C(=O)NCCCC1=CC=CC=C1)SCC(=O)N1CCOCC1 |
Class | Library of small molecule structures |
Ki (µM) | 18.8 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |