HSPMdb Accession NoHSPMDB002470
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name38
IUPAC Name1-Benzyl-2-(2-morpholino-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide
SMILESC(C1=CC=CC=C1)N1C(=NC=C(C1=O)C(=O)NCCCC1=CC=CC=C1)SCC(=O)N1CCOCC1
ClassLibrary of small molecule structures
Ki (µM)18.8
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002470

38

Physicochemical Properties