HSPMdb Accession No | HSPMDB002468 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 34 |
IUPAC Name | Ethyl-2-(1-benzyl-6-oxo-5-(3-phenylpropylcarbamoyl)-1,6-dihydropyrimidin-2-ylthio)acetate |
SMILES | CCN(CC)c1ccc(cc1)C(=O)CSC2=NC=C(C(=O)NCCCc3ccccc3)C(=O)N2Cc4ccccc4 |
Class | Library of small molecule structures |
Ki (µM) | 23.8 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |