HSPMdb Accession NoHSPMDB002467
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name33
IUPAC Name1-Benzyl-2-(2-morpholinoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide
SMILESCCOC(=O)CSC1=NC=C(C(=O)NCCCc2ccccc2)C(=O)N1Cc3ccccc3
ClassLibrary of small molecule structures
Ki (µM)2.3
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002467

33

Physicochemical Properties