HSPMdb Accession No | HSPMDB002466 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 32 |
IUPAC Name | 1-Benzyl-6-oxo-2-(2-oxo-2-(2-(2-phenylacetyl)hydrazinyl)ethylthio)-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide |
SMILES | O=C(NCCCc1ccccc1)C2=CN=C(SCCN3CCOCC3)N(Cc4ccccc4)C2=O |
Class | Library of small molecule structures |
Ki (µM) | 29.5 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |