HSPMdb Accession NoHSPMDB002464
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name30
IUPAC Name1-Benzyl-6-oxo-2-(2-oxo-2-phenylethylthio)-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide
SMILESCOc1ccc(cc1)C(=O)CSC2=NC=C(C(=O)NCCCc3ccccc3)C(=O)N2Cc4ccccc4
ClassLibrary of small molecule structures
Ki (µM)10
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002464

30

Physicochemical Properties