HSPMdb Accession NoHSPMDB002462
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name25
IUPAC Name2-(6-Methyl-2-(2-morpholinoethylthio)pyrimidin-4-yl-thio)-N0-(2-phenylacetyl)acetohydrazide
SMILESCc1cc(SCC(=O)N(N)C(=O)Cc2ccccc2)nc(SCC(=O)c3ccc(cc3)C#N)n1
ClassLibrary of small molecule structures
Ki (µM)12.3
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002462

25

Physicochemical Properties