HSPMdb Accession NoHSPMDB002461
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name24
IUPAC Name2-(6-Methyl-2-(2-morpholino-2-oxoethylthio)pyrimidin-4-ylthio)-N0-(2-phenylacetyl)acetohydrazide
SMILESCc1cc(SCC(=O)N(N)C(=O)Cc2ccccc2)nc(SCCN3CCOCC3)n1
ClassLibrary of small molecule structures
Ki (µM)11.8
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002461

24

Physicochemical Properties