HSPMdb Accession No | HSPMDB002461 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 24 |
IUPAC Name | 2-(6-Methyl-2-(2-morpholino-2-oxoethylthio)pyrimidin-4-ylthio)-N0-(2-phenylacetyl)acetohydrazide |
SMILES | Cc1cc(SCC(=O)N(N)C(=O)Cc2ccccc2)nc(SCCN3CCOCC3)n1 |
Class | Library of small molecule structures |
Ki (µM) | 11.8 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |