HSPMdb Accession NoHSPMDB002459
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name22
IUPAC Name2-(2-(2-(4-Methoxyphenyl)-2-oxoethylthio)-6-methylpyrimidin-4-ylthio)-N0-(2-phenylacetyl)acetohydrazide
SMILESCCN(CC)c1ccc(cc1)C(=O)CSc2nc(C)cc(SCC(=O)N(N)C(=O)Cc3ccccc3)n2
ClassLibrary of small molecule structures
Ki (µM)14.2
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002459

22

Physicochemical Properties