HSPMdb Accession No | HSPMDB002459 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 22 |
IUPAC Name | 2-(2-(2-(4-Methoxyphenyl)-2-oxoethylthio)-6-methylpyrimidin-4-ylthio)-N0-(2-phenylacetyl)acetohydrazide |
SMILES | CCN(CC)c1ccc(cc1)C(=O)CSc2nc(C)cc(SCC(=O)N(N)C(=O)Cc3ccccc3)n2 |
Class | Library of small molecule structures |
Ki (µM) | 14.2 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |