| HSPMdb Accession No | HSPMDB002458 |
| PMID | 28917450 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Plasmodium falciparum |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | 11 |
| IUPAC Name | 2-{[3-oxo-4-(2-phenylethyl)-12-(propan-2-yl)-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.0²,?]trideca-1(9),2(7),5-trien-5-yl]sulfanyl}-N-(4-phenylbutan-2-yl)acetamide |
| SMILES | CC(CCC1=CC=CC=C1)NC(=O)CSC1=NC2=C(C3=C(COC(C3)C(C)C)S2)C(=O)N1CCC1=CC=CC=C1 |
| Class | Library of small molecule structures |
| Ki (µM) | 9 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Cellular Model | P. falciparum |
| Disease | Malaria |
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