HSPMdb Accession NoHSPMDB002456
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name4
IUPAC NameN,N-(5-(Thiazol-2-ylcarbamoyl)-1,3-phenylene)bis(2-phenoxyacetamide)
SMILESCOc1ccc(CNC(=O)C(=O)N/N=C/c2oc(CN[S](=O)(=O)c3ccc(Br)cc3)cc2)cc1
ClassLibrary of small molecule structures
Ki (µM)36
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002456

4

Physicochemical Properties