HSPMdb Accession No | HSPMDB002456 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 4 |
IUPAC Name | N,N-(5-(Thiazol-2-ylcarbamoyl)-1,3-phenylene)bis(2-phenoxyacetamide) |
SMILES | COc1ccc(CNC(=O)C(=O)N/N=C/c2oc(CN[S](=O)(=O)c3ccc(Br)cc3)cc2)cc1 |
Class | Library of small molecule structures |
Ki (µM) | 36 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |