HSPMdb Accession NoHSPMDB002452
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name43
IUPAC Name2-(Morpholinomethyl)-6-oxo-3-phenyl-4,6-dihydropyrimido[2,1-b][1,3]thiazine-7-carboxylic acid
SMILESO1CCN(CC1)CC1=C(CN2C(S1)=NC=C(C2=O)C(=O)O)C2=CC=CC=C2
ClassLibrary of small molecule structures
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002452

43

Physicochemical Properties