HSPMdb Accession NoHSPMDB002451
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name42
IUPAC NameEthyl 2-(2-morpholinoethylthio)-1-(2-oxo-2-phenylethyl)-pyrimidin-4-one-5-carboxylate
SMILESOC(=O)C1=CN=C2SC(=C(CN2C1=O)c3ccccc3)CN4CCOCC4
ClassLibrary of small molecule structures
IC50 (µM)40
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002451

42

Physicochemical Properties