HSPMdb Accession No | HSPMDB002450 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 41 |
IUPAC Name | Ethyl 2-(2-morpholinoethylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxylate |
SMILES | O1CCN(CC1)CCSC=1NC(C(=CN1)C(=O)OCC)=O |
Class | Library of small molecule structures |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |