HSPMdb Accession NoHSPMDB002450
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name41
IUPAC NameEthyl 2-(2-morpholinoethylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxylate
SMILESO1CCN(CC1)CCSC=1NC(C(=CN1)C(=O)OCC)=O
ClassLibrary of small molecule structures
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002450

41

Physicochemical Properties