HSPMdb Accession NoHSPMDB002449
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name40
IUPAC NameEthyl-2-(2-oxo-2-(2-(2-phenylacetyl)hydrazinyl)ethylthio)-pyrimidin-4-one-5-carboxylate
SMILESCCOC(=O)C1=CN=C(NC1=O)SCCN2CCOCC2
ClassLibrary of small molecule structures
IC50 (µM)42
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002449

40

Physicochemical Properties