| HSPMdb Accession No | HSPMDB002441 |
| PMID | 28917450 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Plasmodium falciparum |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | 31 |
| IUPAC Name | 1-Benzyl-2-(2-(4-methoxyphenyl)-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6 dihydropyrimidine-5-carboxamide |
| SMILES | O=C(CSC1=NC=C(C(=O)NCCCc2ccccc2)C(=O)N1Cc3ccccc3)NNC(=O)Cc4ccccc4 |
| Class | Library of small molecule structures |
| IC50 (µM) | 45 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Cellular Model | P. falciparum |
| Disease | Malaria |
Loading Please Wait ...