HSPMdb Accession NoHSPMDB002439
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name26
IUPAC Name2-(2-(2-(4-Cyanophenyl)-2-oxoethylthio)-6-methylpyrimidin-4-yl-thio)-N-(2-phenylacetyl)acetohydrazide
SMILESO=C(CSC1=NC=C(C(=O)NCCCc2ccccc2)C(=O)N1Cc3ccccc3)c4ccccc4
ClassLibrary of small molecule structures
IC50 (µM)37.4
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002439

26

Physicochemical Properties