| HSPMdb Accession No | HSPMDB002438 |
| PMID | 28917450 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Plasmodium falciparum |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | 25 |
| IUPAC Name | 2-(6-Methyl-2-(2-morpholinoethylthio)pyrimidin-4-yl-thio)-N-(2-phenylacetyl)acetohydrazide |
| SMILES | Cc1cc(SCC(=O)N(N)C(=O)Cc2ccccc2)nc(SCC(=O)c3ccc(cc3)C#N)n1 |
| Class | Library of small molecule structures |
| IC50 (µM) | 30.3 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Cellular Model | P. falciparum |
| Disease | Malaria |
Loading Please Wait ...