HSPMdb Accession NoHSPMDB002436
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name23
IUPAC Name2-(2-(2-(4-(Diethylamino)phenyl)-2-oxoethylthio)-6-methylpyrimidin-4-yl-thio)-N-(2-phenylacetyl)acetohydrazide
SMILESCc1cc(SCC(=O)N(N)C(=O)Cc2ccccc2)nc(SCC(=O)N3CCOCC3)n1
ClassLibrary of small molecule structures
IC50 (µM)28.3
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002436

23

Physicochemical Properties