| HSPMdb Accession No | HSPMDB002435 |
| PMID | 28917450 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Plasmodium falciparum |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | 22 |
| IUPAC Name | 2-(2-(2-(4-Methoxyphenyl)-2-oxoethylthio)-6-methylpyrimidin-4-ylthio)-N-(2-phenylacetyl)acetohydrazide |
| SMILES | COC1=CC=C(C=C1)C(CSC1=NC(=CC(=N1)SCC(=O)N(N)C(CC1=CC=CC=C1)=O)C)=O |
| Class | Library of small molecule structures |
| IC50 (µM) | 34.7 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Cellular Model | P. falciparum |
| Disease | Malaria |
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