HSPMdb Accession No | HSPMDB002434 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 13 |
IUPAC Name | S-Benzyl-N-(2-((2-oxo-4-propyl-2H-chromen-7-yl)oxy)acetyl)-cysteine |
SMILES | COc1ccc(cc1)C(=O)CSc2nc(C)cc(SCC(=O)N(N)C(=O)Cc3ccccc3)n2 |
Class | Library of small molecule structures |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |