HSPMdb Accession NoHSPMDB002433
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name12
IUPAC NameN-Benzyl-2-((6-isopropyl-4-oxo-3-phenethyl-3,5,6,8-tetrahydro-4H-pyrano[40,30:4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide
SMILESCCCC1=CC(=O)Oc2cc(OCC(=O)N[C@@H](CSCc3ccccc3)C(O)=O)ccc12
ClassLibrary of small molecule structures
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002433

12

Physicochemical Properties