| HSPMdb Accession No | HSPMDB002431 |
| PMID | 28917450 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Plasmodium falciparum |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | 10 |
| IUPAC Name | N-(3-methoxyphenyl)-2-{[3-oxo-4-(2-phenylethyl)-12-(propan-2-yl)-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.0²,?]trideca-1(9),2(7),5-trien-5-yl]sulfanyl}acetamide |
| SMILES | COC1=CC=CC(NC(=O)CSC2=NC3=C(C4=C(COC(C4)C(C)C)S3)C(=O)N2CCC2=CC=CC=C2)=C1 |
| Class | Library of small molecule structures |
| IC50 (µM) | >100 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Cellular Model | P. falciparum |
| Disease | Malaria |
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