HSPMdb Accession No | HSPMDB002429 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 8 |
IUPAC Name | (Z)-5-((3-(3-Fluoro-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-phenethyl-2-thioxothiazolidin-4-one |
SMILES | CCc1ccc(CSc2ncc(Cl)c(n2)C(=O)NCCC(=O)Nc3ccc(Cl)cc3)cc1 |
Class | Library of small molecule structures |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |