HSPMdb Accession NoHSPMDB002429
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name8
IUPAC Name(Z)-5-((3-(3-Fluoro-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-phenethyl-2-thioxothiazolidin-4-one
SMILESCCc1ccc(CSc2ncc(Cl)c(n2)C(=O)NCCC(=O)Nc3ccc(Cl)cc3)cc1
ClassLibrary of small molecule structures
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002429

8

Physicochemical Properties