HSPMdb Accession NoHSPMDB002428
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name7
IUPAC Name(E)-3-(3-(4-Butoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)-2-cyano-N-(furan-2-ylmethyl)acrylamide
SMILESCCCOc1ccc(cc1F)c2nn(cc2\C=C\3SC(=S)N(CCc4ccccc4)C3=O)c5ccccc5
ClassLibrary of small molecule structures
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002428

7

Physicochemical Properties