HSPMdb Accession No | HSPMDB002426 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 5 |
IUPAC Name | (E)-2-(2-((5-(((4-Bromophenyl)sulfonamido)methyl)furan-2-yl)methylene)hydrazinyl)-N-(4-methoxybenzyl)-2-oxoacetamide |
SMILES | Cc1cc(SCC(=O)N(N)C(=O)Cc2ccccc2)nc(SCC(=O)c3ccccc3)n1 |
Class | Library of small molecule structures |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |