HSPMdb Accession No | HSPMDB002420 |
PMID | 23892893 |
Target | Hsp100 |
Organism | Human |
Cellular activity | Antiproliferative activity |
Compound Name | NMS-873 |
IUPAC Name | 3-[3-cyclopentylsulfanyl-5-(4'-methanesulfonyl-2-methyl-biphenyl-4-yloxymethyl)- [1,2,4]triazol-4-yl]-pyridine |
SMILES | Cc1cc(OCc2nnc(SC3CCCC3)n2c4cccnc4)ccc1c5ccc(cc5)[S](C)(=O)=O |
Class | Small molecule |
IC50 (µM) | 0.7 |
Site of Interaction | Nucleotide binding domain (D2) |
Cellular assay | Luminescence based viability assay |
Cellular Model | HeLa |
Disease | Cancer |