HSPMdb Accession NoHSPMDB002413
PMID23892893
TargetHsp100
OrganismHuman
Cellular activityAntiproliferative activity
Compound NameNMS-485A
IUPAC NameN 4 -benzyl-N 2 -(3-fluorophenyl)quinazoline-2,4-diamine
SMILESFc1cccc(Nc2nc(NCc3ccccc3)c4ccccc4n2)c1
ClassSmall molecule
IC50 (µM)2.8
Site of InteractionNucleotide binding domain (D2)
Cellular assayLuminescence based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB002413

NMS-485A

Physicochemical Properties