HSPMdb Accession NoHSPMDB002412
PMID23892893
TargetHsp100
OrganismHuman
Cellular activityAntiproliferative activity
Compound NameNMS-694
IUPAC NameN,N’-dibenzylquinazoline-2,4-diamine
SMILESC(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4
ClassSmall molecule
IC50 (µM)3.2
Site of InteractionNucleotide binding domain (D2)
Cellular assayLuminescence based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB002412

NMS-694

Physicochemical Properties