HSPMdb Accession NoHSPMDB002411
PMID23892893
TargetHsp100
OrganismHuman
Cellular activityAntiproliferative activity
Compound NameNMS-859
IUPAC Name2-chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]-phenyl}acetamide
SMILESClCC(=O)Nc1cccc(NC2=N[S](=O)(=O)c3ccccc23)c1
ClassSmall molecule
IC50 (µM)3.5
Site of InteractionNucleotide binding domain (D2)
Cellular assayLuminescence based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB002411

NMS-859

Physicochemical Properties