HSPMdb Accession No | HSPMDB002408 |
PMID | 23892893 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Yeast |
Localization | Cytosol, Mitochondria, Endoplasmic reliculum, Nucleous |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | NMS-859 |
IUPAC Name | 2-chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]-phenyl}acetamide |
SMILES | ClCC(=O)Nc1cccc(NC2=N[S](=O)(=O)c3ccccc23)c1 |
Class | Small molecule |
IC50 (µM) | 0.504 uM at 15 minutes |
Site of Interaction | Nucleotide binding domain (D2) |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |