HSPMdb Accession NoHSPMDB002401
PMID23892893
TargetHsp100
HSP Namep97
OrganismYeast
LocalizationCytosol, Mitochondria, Endoplasmic reliculum, Nucleous
Enzymatic activityInhibition of ATPase activity
Compound NameNMS-859
IUPAC Name2-chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]-phenyl}acetamide
SMILESClCC(=O)Nc1cccc(NC2=N[S](=O)(=O)c3ccccc23)c1
ClassSmall molecule
IC50 (µM)0.36 uM at 1 mM ATP
Site of InteractionNucleotide binding domain (D2)
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB002401

NMS-859

Physicochemical Properties