HSPMdb Accession NoHSPMDB002399
PMID23892893
TargetHsp100
HSP Namep97
OrganismYeast
LocalizationCytosol, Mitochondria, Endoplasmic reliculum, Nucleous
Enzymatic activityInhibition of ATPase activity
Compound NameNMS-862
IUPAC Name3-isopropylsulfanyl-5-phenoxymethyl-4-phenyl-4H-[1,2,4]triazole
SMILESCC(C)Sc1nnc(COc2ccccc2)n1c3ccccc3
ClassSmall molecule
IC50 (µM)2.66 uM at 60 uM ATP
Site of InteractionNucleotide binding domain (D2)
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB002399

NMS-862

Physicochemical Properties