HSPMdb Accession No | HSPMDB002399 |
PMID | 23892893 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Yeast |
Localization | Cytosol, Mitochondria, Endoplasmic reliculum, Nucleous |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | NMS-862 |
IUPAC Name | 3-isopropylsulfanyl-5-phenoxymethyl-4-phenyl-4H-[1,2,4]triazole |
SMILES | CC(C)Sc1nnc(COc2ccccc2)n1c3ccccc3 |
Class | Small molecule |
IC50 (µM) | 2.66 uM at 60 uM ATP |
Site of Interaction | Nucleotide binding domain (D2) |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |