HSPMdb Accession No | HSPMDB002398 |
PMID | 23892893 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Yeast |
Localization | Cytosol, Mitochondria, Endoplasmic reliculum, Nucleous |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | NMS-485A |
IUPAC Name | N 4 -benzyl-N 2 -(3-fluorophenyl)quinazoline-2,4-diamine |
SMILES | Fc1cccc(Nc2nc(NCc3ccccc3)c4ccccc4n2)c1 |
Class | Small molecule |
IC50 (µM) | 0.45 uM at 60 uM ATP |
Site of Interaction | Nucleotide binding domain (D2) |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |