HSPMdb Accession No | HSPMDB002397 |
PMID | 23892893 |
Target | Hsp100 |
HSP Name | p97 |
Organism | Yeast |
Localization | Cytosol, Mitochondria, Endoplasmic reliculum, Nucleous |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | NMS-694 |
IUPAC Name | N,N’-dibenzylquinazoline-2,4-diamine |
SMILES | C(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4 |
Class | Small molecule |
IC50 (µM) | 2 uM at 60 uM ATP |
Site of Interaction | Nucleotide binding domain (D2) |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |