HSPMdb Accession NoHSPMDB002397
PMID23892893
TargetHsp100
HSP Namep97
OrganismYeast
LocalizationCytosol, Mitochondria, Endoplasmic reliculum, Nucleous
Enzymatic activityInhibition of ATPase activity
Compound NameNMS-694
IUPAC NameN,N’-dibenzylquinazoline-2,4-diamine
SMILESC(Nc1nc(NCc2ccccc2)c3ccccc3n1)c4ccccc4
ClassSmall molecule
IC50 (µM)2 uM at 60 uM ATP
Site of InteractionNucleotide binding domain (D2)
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB002397

NMS-694

Physicochemical Properties