HSPMdb Accession NoHSPMDB002395
PMID18847196
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameLactone G2
IUPAC Name4-(pent-4-yn-1-yl)-3-pentyloxetan-2-one
SMILESCCCCCC1C(CCCC#C)OC1=O
ClassBeta lactone analogue
IC50 (µM)31
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002395

Lactone G2

Physicochemical Properties