HSPMdb Accession No | HSPMDB002395 |
PMID | 18847196 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | Lactone G2 |
IUPAC Name | 4-(pent-4-yn-1-yl)-3-pentyloxetan-2-one |
SMILES | CCCCCC1C(CCCC#C)OC1=O |
Class | Beta lactone analogue |
IC50 (µM) | 31 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | S. aureus |
Disease | Bacterial infection |