HSPMdb Accession NoHSPMDB002393
PMID18847196
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameLactone D3
IUPAC Name3-(non-8-en-1-yl)-4-(pent-4-yn-1-yl)oxetan-2-one
SMILESC=CCCCCCCCC1C(CCCC#C)OC1=O
ClassBeta lactone analogue
IC50 (µM)6
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002393

Lactone D3

Physicochemical Properties