HSPMdb Accession NoHSPMDB002392
PMID24106749
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameRKS07
IUPAC Name2-acetyl-4-(4-ethynylbenzoyl)-1??,2-thiazetidine-1,1-dione
SMILESCC(=O)N1CC(C(=O)C2=CC=C(C=C2)C#C)S1(=O)=O
ClassChemical compound
IC50 (µM)0.98 at 0.4 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002392

RKS07

Physicochemical Properties