HSPMdb Accession No | HSPMDB002392 |
PMID | 24106749 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | RKS07 |
IUPAC Name | 2-acetyl-4-(4-ethynylbenzoyl)-1??,2-thiazetidine-1,1-dione |
SMILES | CC(=O)N1CC(C(=O)C2=CC=C(C=C2)C#C)S1(=O)=O |
Class | Chemical compound |
IC50 (µM) | 0.98 at 0.4 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | S. aureus |
Disease | Bacterial infection |