HSPMdb Accession NoHSPMDB002390
PMID24106749
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameRKS02
IUPAC Name2-(hex-5-ynoyl)-1??,2-thiazetidine-1,1-dione
SMILESO=C(CCCC#C)N1CCS1(=O)=O
ClassChemical compound
% Enzymatic Inhibition/Fold Change98% at 37ºC for 2 hr
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002390

RKS02

Physicochemical Properties