HSPMdb Accession No | HSPMDB002390 |
PMID | 24106749 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | RKS02 |
IUPAC Name | 2-(hex-5-ynoyl)-1??,2-thiazetidine-1,1-dione |
SMILES | O=C(CCCC#C)N1CCS1(=O)=O |
Class | Chemical compound |
% Enzymatic Inhibition/Fold Change | 98% at 37ºC for 2 hr |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | S. aureus |
Disease | Bacterial infection |