HSPMdb Accession NoHSPMDB002387
PMID24106749
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameDCI
IUPAC Name3,4-Dichloroisocoumarine
SMILESClC1=C(Cl)c2ccccc2C(=O)O1
ClassChemical compound
% Enzymatic Inhibition/Fold Change98% at 37ºC for 2 hr
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002387

DCI

Physicochemical Properties