HSPMdb Accession No | HSPMDB002383 |
PMID | 24106749 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | DCI |
IUPAC Name | 3,4-Dichloroisocoumarine |
SMILES | ClC1=C(Cl)c2ccccc2C(=O)O1 |
Class | Chemical compound |
% Enzymatic Inhibition/Fold Change | 60% at 25ºC for 1 hr |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | S. aureus |
Disease | Bacterial infection |