HSPMdb Accession NoHSPMDB002381
PMID24106749
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameE2
IUPAC Name3-(4-methoxyphenyl)-4-(pent-4-yn-1-yl)oxetan-2-one
SMILESCOc1ccc(cc1)C2C(CCCC#C)OC2=O
ClassChemical compound
% Enzymatic Inhibition/Fold Change98%
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002381

E2

Physicochemical Properties