HSPMdb Accession NoHSPMDB002378
PMID19206121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound NameU1
IUPAC Nametrans-3-(8-Nonen-1-yl)-4-pheneth-1-yloxetan-2-one
SMILESCCC1(CC=CC=C1)[C@@H]2OC(=O)[C@H]2CCCCCCCC=C
ClassBeta lactone analogue
IC50 (µM)7
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002378

U1

Physicochemical Properties