HSPMdb Accession NoHSPMDB002376
PMID22123255
TargetHsp100
HSP NameClpP2
OrganismBacteria
LocalizationCytosol
Cellular activityAntibacterial activity
Compound NameIDR-10011
IUPAC Name1-(3-cyclohexylpropanoyl)-1-[(3,5-difluorophenyl)methyl]-3-[(3S,9S,13S,19S,22R)-19-methyl-2,8,12,18,21-pentaoxo-11-oxa-7,17,20-triazatetracyclo[20.4.0.0³,?.0¹³,¹?]hexacosan-9-yl]urea
SMILESC[C@@H]1NC(=O)[C@@H]2CCCCC2C(=O)[C@@H]2CCCN2C(=O)[C@H](COC(=O)[C@@H]2CCCN2C1=O)NC(=O)N(CC1=CC(F)=CC(F)=C1)C(=O)CCC1CCCCC1
ClassAcyldepsipeptide analogue
Cellular assayBacterial growth inhibition assay (OD based)
MIC/MBC>100 ug/ml (MIC99)
Cellular ModelE. coli
DiseaseBacterial infection

Structure



HSPMDB002376

IDR-10011

Physicochemical Properties