HSPMdb Accession NoHSPMDB002375
PMID22123255
TargetHsp100
HSP NameClpP2
OrganismBacteria
LocalizationCytosol
Cellular activityAntibacterial activity
Compound NameIDR-10001
IUPAC Name1-[(3,5-difluorophenyl)methyl]-1-[(2E)-hept-2-enoyl]-3-[(3S,9S,13S,19S,22R)-19-methyl-2,8,12,18,21-pentaoxo-11-oxa-7,17,20-triazatetracyclo[20.4.0.0³,?.0¹³,¹?]hexacosan-9-yl]urea
SMILESFC=1C=C(C=C(C1)F)CN(C(=O)N[C@@H]1C(N2CCC[C@H]2C(C2CCCC[C@H]2C(N[C@H](C(N2CCC[C@H]2C(OC1)=O)=O)C)=O)=O)=O)C(\C=C\CCCC)=O
ClassAcyldepsipeptide analogue
Cellular assayBacterial growth inhibition assay (OD based)
MIC/MBC>100 ug/ml (MIC99)
Cellular ModelE. coli
DiseaseBacterial infection

Structure



HSPMDB002375

IDR-10001

Physicochemical Properties