| HSPMdb Accession No | HSPMDB002368 |
| PMID | 22123255 |
| Target | Hsp100 |
| HSP Name | ClpP2 |
| Organism | Bacteria |
| Localization | Cytosol |
| Cellular activity | Antibacterial activity |
| Compound Name | ADEP4 |
| IUPAC Name | 1-[(3,5-difluorophenyl)methyl]-3-[(3S,9S,13S,15R,19S,22R)-15,19-dimethyl-2,8,12,18,21-pentaoxo-11-oxa-7,17,20-triazatetracyclo[20.4.0.0³,?.0¹³,¹?]hexacosan-9-yl]-1-[(2E)-hept-2-enoyl]urea |
| SMILES | CCCC\C=C\C(=O)N(CC1=CC(F)=CC(F)=C1)C(=O)N[C@H]1COC(=O)[C@@H]2C[C@@H](C)CN2C(=O)[C@H](C)NC(=O)[C@@H]2CCCCC2C(=O)[C@@H]2CCCN2C1=O |
| Class | Acyldepsipeptide analogue |
| Site of Interaction | Nucleotide binding domain |
| Cellular assay | Bacterial growth inhibition assay (OD based) |
| MIC/MBC | 50 ug/ml (MIC99) |
| Cellular Model | M. tuberculosis (H37Rv) |
| Disease | Tuberculosis |
Loading Please Wait ...