| HSPMdb Accession No | HSPMDB002367 |
| PMID | 22123255 |
| Target | Hsp100 |
| HSP Name | ClpP2 |
| Organism | Bacteria |
| Localization | Cytosol |
| Cellular activity | Antibacterial activity |
| Compound Name | ADEP3 |
| IUPAC Name | 1-(3-cyclohexylpropanoyl)-1-[(3,5-difluorophenyl)methyl]-3-[(3S,9S,13S,15R,19S,22R)-15,19-dimethyl-2,8,12,18,21-pentaoxo-11-oxa-7,17,20-triazatetracyclo[20.4.0.0³,?.0¹³,¹?]hexacosan-9-yl]urea |
| SMILES | C[C@@H]1C[C@@H]2N(C1)C(=O)[C@H](C)NC(=O)[C@@H]1CCCCC1C(=O)[C@@H]1CCCN1C(=O)[C@H](COC2=O)NC(=O)N(CC1=CC(F)=CC(F)=C1)C(=O)CCC1CCCCC1 |
| Class | Acyldepsipeptide analogue |
| Site of Interaction | Nucleotide binding domain |
| Cellular assay | Bacterial growth inhibition assay (OD based) |
| MIC/MBC | 100 ug/ml (MIC99) |
| Cellular Model | M. tuberculosis (H37Rv) |
| Disease | Tuberculosis |
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