HSPMdb Accession No | HSPMDB002357 |
PMID | 25944857 |
Target | Hsp100 |
HSP Name | ClpP1P2 |
Organism | Bacteria |
Localization | Cytosol |
Cellular activity | Antibacterial activity |
Compound Name | 100, (Bortezomib) |
IUPAC Name | [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid |
SMILES | B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
Class | PHARMAKON1600 library |
Site of Interaction | Nucleotide binding domain |
Percentage Cell Growth Inhibition | 30% |
Cellular assay | Bacterial growth inhibition assay (OD based) |
Cellular Model | M. smegmatis (mc2155) |
Disease | Tuberculosis |