HSPMdb Accession No | HSPMDB002354 |
PMID | 26566002 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | AV287 |
IUPAC Name | N-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-4-(dimethylsulfamoyl)benzamide |
SMILES | CN(C)S(=O)(=O)C1=CC=C(C=C1)C(=O)NCCC1=NC2=C(N1)C=CC=C6 |
Class | COMAS Library |
IC50 (µM) | >95 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (FITC-casein) |
Disease | Bacterial infection |